Contextual Associations During Episodic Recall of Everyday or Virtual Reality (BREAL)
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- STATUS
- Recruiting
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- End date
- Nov 11, 2023
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- participants needed
- 450
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- sponsor
- Hospices Civils de Lyon
Summary
The project is dedicated to development of new paradigms to investigate memory and attention in the rich and realistic environments. The investigator will use modern interactive digital technologies for encoding complex episodes either using mobile phone technology in everyday life or using a virtual reality life-like simulation.
He aims to characterize the role of the medial temporal lobe and prefrontal cortex during recall of naturalistic episodic experiences, using functional neuroimaging (fMRI) in healthy participants. The secondary aim is assess how the allocation of attention during memory encoding contribute to mechanisms of the subsequent recall. He will achieve this by monitoring gaze direction during encoding and by analyzing the retrieval data as a function of the elements that participants attended / fixated during encoding.
The protocol will involve, first, behavioral testing of memory performance with encoding in the real-life or in virtual reality, followed by the main hypothesis testing phase when fMRI will be used to measure brain activity during retrieval.
Details
| Condition | Healthy Volunteers |
|---|---|
| Treatment | Functional brain imaging without any contrast agent |
| Clinical Study Identifier | NCT03286387 |
| Sponsor | Hospices Civils de Lyon |
| Last Modified on | 21 March 2022 |
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