Last updated on July 2019

Study To Evaluate The Efficacy And Safety Of Oral PF-06651600 And PF 06700841 In Subjects With Moderate To Severe Crohn's Disease


Brief description of study

The objectives of this study are to evaluate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06651600 (200 mg for 8 weeks followed by 50 mg for 4 weeks) dosed once daily and PF-06700841 (60 mg for 12 weeks) dosed once daily during an induction period of 12 weeks, followed by an open label extension period at doses of 50 mg and 30 mg of PF 06651600 and PF 06700841, respectively, for 52 weeks.

Clinical Study Identifier: NCT03395184

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Dothan Surgery Center

Dothan, AL United States
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Brighton Surgical Center

Beverly Hills, CA United States
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Entertainment Medical Group

Los Angeles, CA United States
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Gastro Florida

Clearwater, FL United States
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West Coast Endoscopy Center

Clearwater, FL United States
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Millenia Surgery Center

Orlando, FL United States
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HMD Research LLC

Orlando, FL United States
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CroNOLA, LLC

Houma, LA United States
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Chevy Chase Endoscopy Center

Chevy Chase, MD United States
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Capitol Research

Rockville, MD United States
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Brigham and Women's Hospital

Chestnut Hill, MA United States
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UMass Memorial Medical Center

Worcester, MA United States
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Caro Health Plaza

Caro, MI United States
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Eastside Endoscopy Center

Macomb, MI United States
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Eastside Endoscopy Center

Saint Clair Shores, MI United States
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UNC Hospitals

Chapel Hill, NC United States
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PMG Research of Winston-Salem, LLC

Winston-Salem, NC United States
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Holston Medical Group

Kingsport, TN United States
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Holston Valley Surgery Center

Kingsport, TN United States
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Envision Imaging (CXR)

Arlington, TX United States
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Pearland Surgery Center

Houston, TX United States
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Lonestar Endoscopy, LLP

Southlake, TX United States
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Verity Research, Inc.

Fairfax, VA United States
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Mater Misericordiae Ltd

South Brisbane, Australia
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Medialpharma s.r.o.

Hradec Kralove, Czechia
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Kangbuk Samsung Hospital

Seoul, Korea, Republic of
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ETG Kielce

Kielce, Poland
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Lexmedica

Wroclaw, Poland
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Clinic of FSBEI HE KSMU MoH RF

Krasnodar, Russian Federation
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LLC "Olla-Med"

Moscow, Russian Federation
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LLC "New Clinic"

Pyatigorsk, Russian Federation
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Limited Liability Company "RIAT"

Saint-Petersburg, Russian Federation
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ENDOMED, s.r.o.

Vranov nad Toplou, Slovakia
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Al Baraha Hospital - MOH

Dubai, United Arab Emirates
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Emirates Specialty Hospital

Dubai, United Arab Emirates
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HRMD Research

Dallas, TX United States
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IRCCS Saverio de Bellis

Castellana Grotte, Italy
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Front Range Endoscopy Center

Colorado Springs, CO United States
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Recruitment Status: Open


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