Last updated on January 2019

Induction Study #1 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease


Brief description of study

This is a Phase 3, randomized, double-blind, placebo-controlled study to explore the effect of oral ozanimod as an induction treatment for subjects with moderately to severely active Crohn's Disease.

Clinical Study Identifier: NCT03440372

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Holland Center for Family Health
Peoria, AZ United States
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Arkansas Gastroenterology, P.A.
North Little Rock, AR United States
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Sharp Chula Vista Medical Center
Chula Vista, CA United States
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Valley View Internal Medicine
Garden Grove, CA United States
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Children's Hospital of Los Angeles
Los Angeles, CA United States
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Gastrointestinal Biosciences
Los Angeles, CA United States
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ABS Health, LLC
Mission Viejo, CA United States
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Alliance Clinical Research
Oceanside, CA United States
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Palo Alto Center-Palo Alto Medical Foundation Research Institute
Palo Alto, CA United States
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Inland Empire Liver Foundation
Rialto, CA United States
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Medical Associates Research Group
San Diego, CA United States
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San Diego Clinical Trials
San Diego, CA United States
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Yale University
New Haven, CT United States
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Gastro Florida
Clearwater, FL United States
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Floridian Clinical Research LLC
Hialeah, FL United States
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Harmony Medical Research Institute
Hialeah, FL United States
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The Center for Gastrointestinal Disorders
Hollywood, FL United States
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Vista Health Research
Homestead, FL United States
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Florida Center for Gastroenterology
Largo, FL United States
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Nova Clinical Research Center LLC
Miami, FL United States
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LCC Medical Research Institute, LLC
Miami, FL United States
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Research Associates of South Florida LLC
Miami, FL United States
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Advanced Research for Health Improvement
Naples, FL United States
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HMD Research LLC
Orlando, FL United States
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Advanced Medical Research Center
Port Orange, FL United States
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Asclepes Research Centers
Weeki Wachee, FL United States
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Atlanta Gastroenterology Associates, LLC
Atlanta, GA United States
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Children's Center for Digestive Healthcare
Atlanta, GA United States
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Gastrointestinal Disease Research
Columbus, GA United States
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Gastroenterology Associates Of Central Georgia LLC
Macon, GA United States
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Rush University Medical Center - University Cardiovascular Surgeons
Chicago, IL United States
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Northwestern University
Chicago, IL United States
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Carle Foundation Hospital
Urbana, IL United States
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Iowa Digestive Disease Center
Clive, IA United States
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University of Kentucky Health Care
Lexington, KY United States
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Centex Studies, Inc.
Lake Charles, LA United States
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Nola Research Works
New Orleans, LA United States
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LSU Health Sciences Center Shreveport
Shreveport, LA United States
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Digestive Disease Associates, PA
Catonsville, MD United States
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Harvard Medical School - Beth Israel Deaconess Medical Center (BIDMC) - The Center for Vascular Biol
Boston, MA United States
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Brigham and Women's Hospital - Crohn's and Colitis Center
Chestnut Hill, MA United States
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Medex Research Institute
Caro, MI United States
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Revive Research Institute
Southfield, MI United States
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Washington University School of Medicine
Saint Louis, MO United States
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Advantage Clinical Trials
Bronx, NY United States
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TrialSpark
Brooklyn, NY United States
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NY Scientific
Brooklyn, NY United States
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Northern Medical Group
Fishkill, NY United States
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Adirondack Medical Research Center
Glens Falls, NY United States
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Northwell Health
Great Neck, NY United States
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Cornell University
New York, NY United States
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Lenox Hill Hospital
New York, NY United States
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Circuit Clinical
Orchard Park, NY United States
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Asheville Gastroenterology Associates, P.A.
Asheville, NC United States
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Carolinas HealthCare System Digestive Health
Charlotte, NC United States
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Internal Medicine Research
Charlotte, NC United States
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Carolina Research Center
Greenville, NC United States
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Cleveland Clinic - Taussig Cancer Institute
Cleveland, OH United States
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Great Lakes Gastroenterology
Mentor, OH United States
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Digestive Disease Specialists
Oklahoma City, OK United States
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Oregon Health & Science University
Portland, OR United States
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Penn State University Milton S Hershey Medical Center
State College, PA United States
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Quality Medical Research
Nashville, TN United States
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Vanderbilt University Medical Center
Nashville, TN United States
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Advanced Gastroenterology
Union City, TN United States
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Avant Research Associates, LLC - Austin
Austin, TX United States
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Baylor College of Medicine
Houston, TX United States
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Houston Methodist Hospital
Houston, TX United States
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Biopharma Informatic Inc. Research Center
Houston, TX United States
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GI Specialists of Houston
Houston, TX United States
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Premier Vein and Vascular Center
Houston, TX United States
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Sun Research Institute
San Antonio, TX United States
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Texas Digestive Disease Consultants - Southlake
Southlake, TX United States
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Digestive Health Specialists of Tyler
Tyler, TX United States
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Gastroenterology Associates, PC
Gainesville, VA United States
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Summit Clinical Research, LLC
Petersburg, VA United States
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Virginia Gastroenterology Institute PC
Suffolk, VA United States
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University of Washington Medical Center
Seattle, WA United States
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Dermatologist Specialists of Spokane
Spokane, WA United States
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Aurora Health Care Aurora Research
Grafton, WI United States
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Sanatorio Guemes
Ciudad Autonoma de Buenos Aires, Argentina
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Hospital Privado Centro Medico de Cordoba
Cordoba, Argentina
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Instituto Medico de la Fundacion Estudios Clinicos
Rosario, Argentina
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Universidad Nacional De Rosario - Hospital Provincial Del Centenario
Rosario, Argentina
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Sanatorio 9 de Julio - CICE 9 de Julio
San Miguel de Tucuman, Argentina
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Concord Repatriation General Hospital
Concord, Australia
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Royal Brisbane and Women's Hospital
Herston, Australia
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Princess Alexandra Hospital
Woolloongabba, Australia
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Royal Adelaide Hospital
Adelaide, Australia
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The Queen Elizabeth Hospital
Woodville South, Australia
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Vitebsk Regional Clinical Specialized Center
Vitebsk, Belarus
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Universitair Ziekenhuis Brussel
Brussels, Belgium
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Universitair Ziehenhuis Antwerpen
Edegem, Belgium
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University Hospital Ghent
Ghent, Belgium
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Universitair Ziekenhuis Leuven, Campus Gasthuisberg
Leuven, Belgium
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CHC - Clinique St-Jospeh
Liege, Belgium
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Sart Tilman Hospital Department of Gastroenterology and Hepatology
Seraing, Belgium
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Hospital Centre of Walloon Picarde
Tournai, Belgium
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University Clinical Centre of the Republic of Srpska
Banja Luka, Bosnia and Herzegovina
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University Clinical Hospital Mostar
Mostar, Bosnia and Herzegovina
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Clinical Center University of Sarajevo
Sarajevo, Bosnia and Herzegovina
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CDC - Centro Digestivo de Curitiba
Curitiba, Brazil
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Hospital de Clinicas de Porto Alegre (HCPA)
Porto Algere, Brazil
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Kaiser Clinica
Sao Jose do Rio Preto, Brazil
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Santa Casa De Votuporanga-Philanthropic hospital
Votuporanga, Brazil
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Associacao Hospitalar Beneficente Sao Vicente de Paulo - Hospital Sao Vicente de Paulo
Passo Fundo, Brazil
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Ribeiralo Preto Medical School, University of Salo Paulo
Ribeirao Preto, Brazil
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Universidade Federal do Estado do Rio de Janeiro (UNIRIO) - Hospital Universitario Gaffree e Guinle
Rio de Janeiro, Brazil
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Universidade Federal do Rio de Janeiro (UFRJ)-Hospital Universitario Clementino Fraga Filho (HUCFF)
Rio de Janeiro, Brazil
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CEMEC - Centro Multidisciplinar De Estudos Clanicos
Santo Andre, Brazil
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ACIBADEM City Clinic Medical Center Bregalnitsa
Varna, Bulgaria
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Okanagan Clinical Trials Ltd
Kelowna, BC Canada
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Vancouver Hospital Gastrointestinal Research Unit The Gordon and Leslie Diamond Centre
Vancouver, BC Canada
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Winnipeg Clinic Dermatology Research
Winnipeg, MB Canada
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Viable Clinical Research
Bridgewater, NS Canada
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London Health Sciences Centre, University Hospital
London, ON Canada
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LHSC Victoria Hospital
London, ON Canada
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Clinical Hospital Center Osijek
Osijek, Croatia
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Clinical Hospital Centre Rijeka
Rijeka, Croatia
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Clinical Hospital Center Split
Split, Croatia
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Clinical Hospital Center Sestre milosrdnice Clinic of Internal Diseases
Zagreb, Croatia
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Clinical Hospital Dubrava
Zagreb, Croatia
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University Hospital Centre Zagreb, Clinic of Internal Diseases
Zagreb, Croatia
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St. Anne's University Hospital Brno
Brno, Czechia
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Soukroma Gastroenterologicka ambulance a endoskopie
Most, Czechia
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Krajsk nemocnice Pardubice, Ko n oddelen
Pardubice, Czechia
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University Hospital Pilsen
Plzen, Czechia
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University Hospital Motol
Prague 5, Czechia
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IBD Centrum/ISCARE IVF a.s.
Praha 7, Czechia
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Bispebjerg Hospital
Copenhagen, Denmark
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Nykobing F Hospital
Nykobing F, Denmark
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Interdisciplinary Crohn Colitis Center Rhein Main
Frankfurt, Germany
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Universitaetsklinikum Leipzig AoeR
Leipzig, Germany
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Practice for Gastroenterology and Internal Medicine
Ludwigshafen am Rhein, Germany
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Synesis Research Center
Munich, Germany
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University Hospital Tuebingen, Department of Internal Medicine I
Tuebingen, Germany
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Bat Yamon Medical Center, Clalit Medical Services
Bat Yam, Israel
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Shaare Zedek Medical Center
Jerusalem, Israel
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Galilee Medical Center
Nahariya, Israel
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The Nazareth Hospital E.M.M.S.
Nazareth, Israel
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Chaim Sheba Medical Center
Ramat Gan, Israel
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Kaplan Medical Center
Rechovot, Israel
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University Polyclinic Hospital of Bari
Bari, Italy
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Polyclinic S. Orsola-Malpighi
Bologna, Italy
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Civil Hospital of Brescia
Brescia, Italy
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University Hospital Mater Domini
Catanzaro, Italy
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"Ss. Annunziata" Policlinic of Chieti
Chieti, Italy
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University Polyclinic Hospital G. Martino
Messina, Italy
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Maggiore Polyclinic Hospital, IRCCS Ca' Granda
Milano, Italy
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Humanitas Research Hospital - Humanitas Mirasole S.p.A
Milan, Italy
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Local Healthcare Company of Monza ASST Monza
Monza, Italy
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United Hospitals Villa Sofia Cervello
Palermo, Italy
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Polyclinic San Matteo IRCCS
Pavia, Italy
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Univerisity Polyclinic Foundation Agostino Gemelli
Roma, Italy
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Azienda Ospedaliera San Camillo Forlanini
Rome, Italy
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Integrated University Hospital Santa Maria della Misericordia of Udine
Udine, Italy
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A.O. Universitaria Fondazione Macchi
Varese, Italy
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Sacred Heart Don Calabria
Verona, Italy
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Korea University Medical Center - Korea University Ansan Hospital
Ansan, Korea, Republic of
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Hanyang University Guri Hospital
Guri-si, Korea, Republic of
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Seoul National University Bundang Hospital
Seongnam-si, Korea, Republic of
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Severance Hospital
Seoul, Korea, Republic of
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Samsung Medical Center
Seoul, Korea, Republic of
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Kangbuk Samsung Hospital
Seoul, Korea, Republic of
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Ewha Womans University Mokdong Hospital
Seoul, Korea, Republic of
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P. Stradins Clinical University Hospital
Riga, Latvia
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Digestive Diseases Center Gastro
Riga, Latvia
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Riga East Clinical University Hospital clinic Gailezers
Riga, Latvia
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Hospital Dalinde - CECRA Clinica Especializada en Colon, Recto y Ano
Delegacion Cuauhtemoc, Mexico
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Investigacion Biomedica para el desarrollo de Farmacos, S.A. de C.V.
Zapapan, Mexico
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Centro Regiomontano de Estudios Clinicos Roma SC.
Monterrey, Mexico
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Instituto Tecnol gico y de Estudios Superiores de Monterrey
Monterrey, Mexico
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Hospital Christus Muquerza del Parque S.A. de C.V.
Chihuahua, Mexico
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Centro de Investigacion Clinica Acelerada (CICA) S.C.
Mexico, Mexico
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Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Tlalpan, Mexico
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"Sfanta Treime" Clinical Municipal Hospital, Department of Proctology
Chisinau, Moldova, Republic of
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Clinical Hospital of the Ministry of Health, Department of Endoscopic Surgery
Chisinau, Moldova, Republic of
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"Sf. Arhanghel Mihail" Municipal Clinical Hospital
Chisinau, Moldova, Republic of
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Republican Clinical Hospital, Department of Colorectal Surgery
Chisinau, Moldova, Republic of
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Republican Clinical Hospital, Department of Gastroenterology
Chisinau, Moldova, Republic of
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Lovisenberg Diakonale Sykehus
Oslo, Norway
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SP ZOZ Wojewodzki Szpital Zespolony im. J. Sniadeckiego
Bialystok, Poland
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Medical Services Center MaxMed
Bochnia, Poland
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Kornel Gibinski Independent Public Central Clinical Hospital in Katowice
Katowice, Poland
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GLOBE Clinical Research Sp. z o.o. LLC
Klodzko, Poland
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PLEJADY Sp. z o.o. (LLC) Medical Centre
Krakow, Poland
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Landa Specialist Doctor's Offices
Krakow, Poland
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Krakow Medical Center LLC
Krakow, Poland
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Santa Familia Centrum Badan, Profilaktyki i Leczenia
Lodz, Poland
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GASTROMED Kopon, Zmudzinski and Partners Specialist Centre for Gastroenterology and Endoscopy, Spe
Torun, Poland
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H-T. Medical Center Sp. z o.o. LLC Limited Partnership
Tychy, Poland
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Polimedica
Ul. Piotrkowska 177, Poland
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Maternal Pediatric and Adolescent Healthcare Centre
Warsaw, Poland
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Niepubliczny Zaklad Opieki Zdrowotnej VIVAMED
Warszawa, Poland
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Dr. Carol Davila Central Military Emergency Clinical Hospital
Bucharest, Romania
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Fundeni Clinical Institute
Bucharest, Romania
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Bucharest University Emergency Hospital, Department of Internal Medicine II
Bucharest, Romania
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Center of Diagnosis and Treatment Provita
Bucharest, Romania
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Hyperclinic MedLife Grivita
Bucharest, Romania
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Craiova County Emergency Clinical Hospital
Craiova, Romania
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Colentina Clinical Hospital
Napoca, Romania
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Targu Mures County Emergency Clinical Hospital
Targu Mures, Romania
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Irkutsk State Medical Academy of Postgraduate Education
Irkutsk, Russian Federation
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Moscow Clinical Scientific and Practical Center
Moscow, Russian Federation
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Republican Hospital na VA Baranov
Petrozavodsk, Russian Federation
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Evromedservis
Pushkin, Russian Federation
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Pyatigorsk City Hospital 2
Pyatigorsk, Russian Federation
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Rostov State Medical University
Rostov-on-Don, Russian Federation
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Medical Center Reavita Med Spb LLC
Saint Petersburg, Russian Federation
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Samara Station Railway Clinical Hospital under OAO Russian Railways
Samara, Russian Federation
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Clinical and Diagnostic Center with an outpatient department under the Presidential Executive Office
St. Petersburg, Russian Federation
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SPb SBIH City Hospital of Saint Martyr Elizaveta
St. Petersburg, Russian Federation
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SPb SBIH City Hospital # 9
St. Petersburg, Russian Federation
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City Clinical Hospital #21
Ufa, Russian Federation
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Novgorod Regional Clinical Hospital
Veliky Novgorod, Russian Federation
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King Fahad Specialist Hospital
Dammam, Saudi Arabia
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King Abdul Aziz University Hospital
Jeddah, Saudi Arabia
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King Saud Medical Complex
Riyadh, Saudi Arabia
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King Fahad National Guard Hospital
Riyadh, Saudi Arabia
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General University Hospital of Alicante
Alicante, Spain
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University Hospital Germans Trias i Pujol
Badalona, Spain
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University Hospital of the Canary Islands (HUC) La Laguna
La Laguna, Spain
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University Hospital de La Princesa
Madrid, Spain
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University Hospital La Paz
Madrid, Spain
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University Hospital Virgen Macarena
Sevilla, Spain
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University Hospital Virgen del Rocio
Sevilla, Spain
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Viladecans Hospital
Viladecans, Spain
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Cantonal Hospital Saint Gallen
St.Gallen, Switzerland
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University Hospital Zurich
Zurich, Switzerland
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Bulent Ecevit Universitesi Uygulama ve Arastirma Hastanesi
Kozlu, Taiwan
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Ankara University Medical Faculty Cebeci Hospital
Ankara, Turkey
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Uludag Universitesi Tip Fakultesi
Bursa, Turkey
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Bezmialem Foundation University Medical Faculty
Istanbul, Turkey
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Kocaeli Derince Training and Research Hospital
Kocaeli, Turkey
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Karadeniz Teknik Universitesi Tip Fakultesi Farabi Hastanesi
Trabzon, Turkey
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Si Institute Of Gastroenterology Of Namsu Dept Of Stomach And Duodenum Diseases
Dnipropetrovsk, Ukraine
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Ivano-Frankivsk Central City Clinical Hospital
Ivano-Frankivsk, Ukraine
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Medical Center Consilium Medical
Kyiv, Ukraine
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Associate Director Clinical Trial Disclosure

Kyiv Regional Hospital #2
Kyiv, Ukraine
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Associate Director Clinical Trial Disclosure

Public City Clinical Hospital of Emergency Medical Care
Lviv, Ukraine
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Associate Director Clinical Trial Disclosure

Bristol Royal Infirmary
Bristol, United Kingdom
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Associate Director Clinical Trial Disclosure

Ulster Hospital
Dundonald, United Kingdom
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Associate Director Clinical Trial Disclosure

Queen Elizabeth University Hospital
Glasgow, United Kingdom
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Associate Director Clinical Trial Disclosure

Victoria Hospital Blackpool
Lancashire Blackpool, United Kingdom
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Associate Director Clinical Trial Disclosure

Royal London Hospital
London, United Kingdom
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Associate Director Clinical Trial Disclosure

St Thomas' Hospital
London, United Kingdom
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Associate Director Clinical Trial Disclosure

John Radcliffe Hospital
Oxford, United Kingdom
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Associate Director Clinical Trial Disclosure

Southampton General Hospital
Southampton, United Kingdom
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Associate Director Clinical Trial Disclosure

Torbay Hospital
Torquay, United Kingdom
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Associate Director Clinical Trial Disclosure

Universitaetsklinikum Ulm
Ulm, Germany
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Associate Director Clinical Trial Disclosure

Elite Clinical Studies, LLC
Phoenix, AZ United States
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Associate Director Clinical Trial Disclosure

VA Northern California Health Care System
Mather, CA United States
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Associate Director Clinical Trial Disclosure

Qway Research LLC
Hialeah, FL United States
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Associate Director Clinical Trial Disclosure

Consultative Gastroenterology
Atlanta, GA United States
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Associate Director Clinical Trial Disclosure

Great Lakes Medical Research, LLC
Beachwood, OH United States
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Associate Director Clinical Trial Disclosure

University of Oklahoma Health Sciences Center
Oklahoma City, OK United States
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Associate Director Clinical Trial Disclosure

Penn State Milton S Hershey Medical Center
Hershey, PA United States
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Associate Director Clinical Trial Disclosure

Harry Perkins Medical Research Institute, Fiona Stanley Hospital
Murdoch, Australia
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Associate Director Clinical Trial Disclosure

Multiprofile Hospital for Active Treatment Medline
Plovdiv, Bulgaria
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Associate Director Clinical Trial Disclosure

University Multiprofile Hospital for Active Treatment Sveti Ivan Rilski EAD
Sofia, Bulgaria
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Associate Director Clinical Trial Disclosure

University Multiprofile Hospital for Active Treatment ACIBADEM City Clinic Sofia
Sofia, Bulgaria
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Associate Director Clinical Trial Disclosure

Gastroenterology Am Bayerischen Platz
Berlin, Germany
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Associate Director Clinical Trial Disclosure

Agaplesion Markus Krankenhaus
Frankfurt, Germany
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Associate Director Clinical Trial Disclosure

University Hospital Hamburg-Eppendorf
Hamburg, Germany
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Associate Director Clinical Trial Disclosure

St Vincent's University Hospital
Dublin 4, Ireland
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Associate Director Clinical Trial Disclosure

Provincial Specialist Hospital in Olsztyn
Olsztyn, Poland
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Associate Director Clinical Trial Disclosure

V.T. Zaitsev Institute of General and Emergency Surgery
Kharkiv, Ukraine
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Associate Director Clinical Trial Disclosure

Kyiv Regional Clinical Hospital
Kyiv, Ukraine
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Associate Director Clinical Trial Disclosure

Volyn Regional Clinical Hospital
Lutsk, Ukraine
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Associate Director Clinical Trial Disclosure

Ternopil City Public Emergency Medical Care Hospital
Ternopil, Ukraine
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Associate Director Clinical Trial Disclosure

Ok Clinic Medical Center within International Institute of Clinical Trials, LLC
Kyiv, Ukraine
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Associate Director Clinical Trial Disclosure

Great Lakes Medical Research, LLC
Warren, OH United States
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Associate Director Clinical Trial Disclosure

Chernivtsi Regional Clinical Hospital
Chernivtsi, Ukraine
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Associate Director Clinical Trial Disclosure

Cemic Saavedra
Ciudad Autónoma De Buenos Aires, Argentina
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Associate Director Clinical Trial Disclosure

Toronto Digestive Disease Associates Inc
Vaughan, ON Canada
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Associate Director Clinical Trial Disclosure

Hepato-Gastroenterologie HK, s. r. o.
Hradec Králové, Czechia
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Associate Director Clinical Trial Disclosure

Akershus University Hospital
Lørenskog, Norway
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Recruitment Status: Open


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