Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

  • End date
    Feb 14, 2024
  • participants needed
  • sponsor
    Memorial Sloan Kettering Cancer Center
Updated on 13 July 2022
bone graft


The purpose of this study is to look at the amount of function that returns in participants that have reconstruction with bone graft or artificial device and in participants who have tumor surgery plus regenerative osseous surgery.

The study will look at the level of function for a period of 3 years after the surgery. Another purpose of this study is to look at how well the bone heals in participants undergoing regenerative surgery

Condition Bone Sarcoma, Osteosarcoma, Chondrosarcoma, Ewing's Sarcoma, Osseous Sarcoma, Bone Neoplasm
Treatment Range of Motion, Toronto Extremity Salvage Score, Musculoskeletal Tumor Society Score, Timed Get Up and Go Test, Orthogonal Radiographs, Weight Bearing for lower extremities only, Osteocalcin, Osteocalcin, Amino terminal propepetide of type 1 collagen, N-telopeptide of type 1 collagen
Clinical Study IdentifierNCT03442465
SponsorMemorial Sloan Kettering Cancer Center
Last Modified on13 July 2022


Yes No Not Sure

Inclusion Criteria

All patients undergoing reconstructive surgery for new bone sarcomas on the orthopaedic surgery service at MSK
Current or prior history of primary sarcomas involving osseous structures, including all subtypes
Confirmation of diagnosis that has been performed by the MSK's Department of Pathology via direct review of tissue/slides
Patients must read and understand English
Age >/=4

Exclusion Criteria

Patients with ECOG status score of 4 or 5
Patients that weight <17 kilograms
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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