Links Between Perception of Temporal Order Judgment and Causality in Schizophrenia (TOCAS)

  • STATUS
    Recruiting
  • days left to enroll
    27
  • participants needed
    60
  • sponsor
    Hôpital le Vinatier
Updated on 4 October 2022
psychiatric disorder
psychotropic drugs
delusions
Accepts healthy volunteers

Summary

People with schizophrenia show disturbances in the perception of time. Among these alterations are the perturbations of the temporal order judgment. They are characterized by the fact that, as opposed to the general population, people with schizophrenia require a longer time interval between two successive stimuli to estimate which of the two events appeared first. If these alterations are now well documented, their consequences remain little explored. Among these consequences could however appear distortions of the judgment of causality (likely to underlie certain delusional interpretations) as well as a distressing experience of loss of the continuity of the lived experience (that could contribute to the alterations basic of self-awareness).

Description

The objective of our work lies in the study of the links between temporal sequencing, subjective perception of time and causality.

To carry out this work, the investigators will rely on an experimental paradigm (derived from Michotte's paradigm) which makes it possible to explore the links between temporal sequencing and perception of causality, validated in the normal subject. subjective consequences of these alterations will be explored using a phenomenological-inspired clinical scale (EAWE time-scale items)

Details
Condition Schizophrenia
Treatment Performances of patients and controls on temporal task
Clinical Study IdentifierNCT03432000
SponsorHôpital le Vinatier
Last Modified on4 October 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Subjects with schizophrenia
Age from 18 to 45 years
Diagnosis of schizophrenia according to DSM V criteria
French mother tongue
Psychotropic treatment unchanged during the month preceding the inclusion
Stable symptomatology
Normal or corrected visual acuity (> 0.8 at Snellen scale) and normal color vision
Patients who gave informed consent to participate in the study
Control subjects (healthy volunteers)
Age from 18 to 45 years
Absence of neurological and psychiatric disorders
French mother tongue

Exclusion Criteria

Recent addiction and abuse of cannabis or any other substance (according to DSM V criteria)
Neurological disorders of vascular, infectious or neurodegenerative origin
Taking somatic drugs with a cerebral or mental impact (eg corticosteroids)
Disabling sensory disturbances, and in particular visual acuity
Participation in a Neuro Cognitive Remediation Program
Schizophrenia resistant to neuroleptic treatments
Persons protected by law (pregnant women, minors, major under guardianship ...)
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note