Pupillometry in Horner's Syndrome

  • STATUS
    Recruiting
  • End date
    Dec 31, 2022
  • participants needed
    135
  • sponsor
    University of Zurich
Updated on 25 February 2022
ischemic stroke
acute stroke

Summary

Horner's syndrome (HS) is a result of interruption of the sympathetic innervation to the eye and ocular adnexa, which can occur due to carotid artery dissection (CAD), along which the sympathetic nerve fibers travel to reach the eye. Dissection of the carotid artery is one of the etiologies for ischemic stroke in young patients.

In our current study, we will explore the diagnostic accuracy of automated binocular pupillometry in the diagnosis or HS, and its potential in identifying dissection of the carotid artery in patients of young age who suffer ischemic stroke.

Details
Condition Horner's Syndrome, Stroke, Dissection Carotid Artery
Treatment Automated pupillometry
Clinical Study IdentifierNCT02978079
SponsorUniversity of Zurich
Last Modified on25 February 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Adults 60 years of age or younger
Acute stroke (less than 72 hours from admission)
Informed Consent as documented by signature (Appendix Informed Consent Form)
Ability to understand the study information and consent form

Exclusion Criteria

known history of HS
Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc
Medications affecting pupillary response
History of ocular surgery affecting the pupil
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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