Last updated on August 2019

Mupirocin-Iodophor ICU Decolonization Swap Out Trial


Brief description of study

The Swap Out Trial is a cluster randomized controlled trial of HCA hospitals, evaluating the non-inferiority of two decolonization regimens:

Arm 1 Routine Care: ICU nasal decolonization with mupirocin twice daily for 5 days in the context of chlorhexidine for daily bathing; Arm 2 Intervention: ICU nasal decolonization with iodophor twice daily for 5 days in the context of chlorhexidine for daily bathing Note: that enrolled "subjects" represents 137 individual HCA Hospitals (representing ~235 ICUs) that have been randomized.

Clinical Study Identifier: NCT03140423

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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