Last updated on August 2018

Mupirocin-Iodophor ICU Decolonization Swap Out Trial


Brief description of study

The Swap Out Trial is a cluster randomized controlled trial of HCA hospitals, evaluating the non-inferiority of two decolonization regimens:

Arm 1 Routine Care: ICU nasal decolonization with mupirocin twice daily for 5 days in the context of chlorhexidine for daily bathing; Arm 2 Intervention: ICU nasal decolonization with iodophor twice daily for 5 days in the context of chlorhexidine for daily bathing Note: that enrolled "subjects" represents 137 individual HCA Hospitals (representing ~235 ICUs) that have been randomized.

Clinical Study Identifier: NCT03140423

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Riverside Community Hospital

Riverside, CA United States
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Good Samaritan Hospital

San Jose, CA United States
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Los Robles Regional Medical Center

Thousand Oaks, CA United States
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Swedish Medical Center

Denver, CO United States
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Sky Ridge Medical Center

Denver, CO United States
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Rose Medical Center

Denver, CO United States
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JFK Medical Center

Atlantis, FL United States
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Aventura Hospital

Aventura, FL United States
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Blake Medical Center

Bradenton, FL United States
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Brandon Regional

Brandon, FL United States
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Oak Hill Hospital

Brooksville, FL United States
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Englewood Community Hospital

Englewood, FL United States
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Lawnwood Regional Medical Center

Fort Pierce, FL United States
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Fort Walton Medical Center

Fort Walton Beach, FL United States
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Memorial Hospital Jacksonville

Jacksonville, FL United States
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Poinciana Medical Center

Kissimmee, FL United States
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Lake City Medical Center

Lake City, FL United States
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Largo Medical Center

Largo, FL United States
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Palms West Hospital

Loxahatchee Groves, FL United States
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Northwest Medical Center

Margate, FL United States
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Mercy Hospital

Miami, FL United States
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Twin Cities Hospital

Niceville, FL United States
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Raulerson Hospital

Okeechobee, FL United States
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Orange Park Medical Center

Orange Park, FL United States
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Gulf Coast Medical Center

Panama City, FL United States
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West Florida Hospital

Pensacola, FL United States
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Plantation General Hospital

Plantation, FL United States
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Fawcett Memorial Hospital

Port Charlotte, FL United States
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St. Lucie Medical Center

Port Saint Lucie, FL United States
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Northside Hospital

Saint Petersburg, FL United States
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St. Petersburg General Hospital

Saint Petersburg, FL United States
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Doctor's Hospital Sarasota

Sarasota, FL United States
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South Bay Hospital

Sun City Center, FL United States
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Capital Regional Medical Center

Tallahassee, FL United States
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Medical Center of Trinity

Trinity, FL United States
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JFK Medical Center - North Campus

West Palm Beach, FL United States
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Doctor's Hospital Augusta

Augusta, GA United States
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Cartersville Medical Center

Cartersville, GA United States
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Fairview Park

Dublin, GA United States
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Eastside Medical Center

Snellville, GA United States
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West Valley Medical Center

Caldwell, ID United States
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Eastern Idaho Regional

Idaho Falls, ID United States
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Terre Haute Regional Hospital

Terre Haute, IN United States
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Menorah Medical Center

Overland Park, KS United States
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Wesley Medical Center

Wichita, KS United States
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Wesley Woodlawn Hospital

Wichita, KS United States
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Greenview Regional Hospital

Bowling Green, KY United States
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Rapides Regional Medical Center

Alexandria, LA United States
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Garden Park Medical Center

Gulfport, MS United States
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Centerpoint Medical Center

Independence, MO United States
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Research Medical Center

Kansas City, MO United States
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Lee's Summit Medical Center

Lee's Summit, MO United States
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Mountainview Hospital - Vegas

Las Vegas, NV United States
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Parkland Medical Center

Derry, NH United States
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Portsmouth Regional Hospital

Portsmouth, NH United States
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Spotsylvania Regional Medical Center

Fredericksburg, PA United States
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Trident Regional Medical Center

Charleston, SC United States
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Summerville Medical Center

Summerville, SC United States
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Colleton Medical Center

Walterboro, SC United States
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Parkridge Medical Center

Chattanooga, TN United States
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Parkridge East Hospital

Chattanooga, TN United States
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Hendersonville Medical Center

Hendersonville, TN United States
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Summit Medical Center

Hermitage, TN United States
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Stonecrest Medical Center

Nashville, TN United States
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Centennial Medical Center

Nashville, TN United States
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Skyline Medical Center

Nashville, TN United States
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Southern Hills Medical Center

Nashville, TN United States
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Medical Center of Arlington

Arlington, TX United States
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South Austin Hospital

Austin, TX United States
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Valley Regional Medical Center

Brownsville, TX United States
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Las Palmas Medical Center

El Paso, TX United States
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Del Sol Medical Center

El Paso, TX United States
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West Houston Medical Center

Houston, TX United States
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Kingwood Medical Center

Kingwood, TX United States
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Medical Center of Lewisville

Lewisville, TX United States
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Medical Center of McKinney

McKinney, TX United States
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North Hills Hospital

North Richland Hills, TX United States
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Bayshore Medical Center

Pasadena, TX United States
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Medical Center of Plano

Plano, TX United States
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Round Rock Hospital

Round Rock, TX United States
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Metropolitan Methodist Hospital

San Antonio, TX United States
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Methodist Hospital

San Antonio, TX United States
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Methodist Stone Oak Hospital

San Antonio, TX United States
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Methodist Texsan Hospital

San Antonio, TX United States
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Northeast Methodist Hospital

San Antonio, TX United States
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Mainland Medical Center

Texas City, TX United States
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Lakeview Hospital

Bountiful, UT United States
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LewisGale Hospital - Montgomery

Blacksburg, VA United States
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John Randolph Medical Center

Hopewell, VA United States
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Reston Hospital

Reston, VA United States
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LewisGale Medical Center

Salem, VA United States
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Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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