Induction Chemotherapy Followed by Radiotherapy Alone or Concurrent Chemoradiotherapy in Nasopharyngeal Carcinoma (IRCNPC)
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- STATUS
- Recruiting
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- End date
- Dec 21, 2024
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- participants needed
- 440
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- sponsor
- Zhejiang Cancer Hospital
Summary
In this study, the investigators aim to compare the progression-free survival (PFS) and side effects of radiotherapy (RT) and concurrent chemoradiotherapy (CCRT) in locoregionally advanced nasopharyngeal carcinoma (NPC) patients with a satisfactory tumor response (complete response or partial response) after neoadjuvant chemotherapy (NACT).
Description
In this study, the investigators aim to compare the survival outcomes and side effects of radiotherapy (RT) and concurrent chemoradiotherapy (CCRT) in locoregionally advanced nasopharyngeal carcinoma (NPC) patients with a satisfactory tumor response (complete response or partial response) after neoadjuvant chemotherapy (NACT) with Docetaxel and Cisplatin treated using intensity-modulated radiotherapy (IMRT) or tomotherapy (TOMO).
Details
| Condition | Locally Advanced Nasopharyngeal Carcinoma |
|---|---|
| Treatment | cisplatin, docetaxel, Chemotherapy, IMRT/TOMO |
| Clinical Study Identifier | NCT03015727 |
| Sponsor | Zhejiang Cancer Hospital |
| Last Modified on | 25 February 2022 |
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