Feasibility Study of Using Molecular Fluorescence Guided Surgery in Endometriosis

  • participants needed
  • sponsor
    University Medical Center Groningen
Updated on 8 November 2020


Incomplete resection of endometriosis lesions often results in recurrence of symptoms and the need for repeated surgery, with considerable associated morbidity. The aim of this pilot project is to determine the feasibility of fluorescence imaging to improve the treatment of endometriosis in the future.

Treatment Bevacizumab-800CW
Clinical Study IdentifierNCT02975219
SponsorUniversity Medical Center Groningen
Last Modified on8 November 2020

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Inclusion Criteria

Is your age between 18 yrs and 99 yrs?
Gender: Male or Female
Do you have Endometriosis?
Females aged 18 years
Scheduled for surgery for the treatment of endometriosis
WHO performance score of 0-2
Written informed consent
For female subjects who are of childbearing potential, are premenopausal with
intact reproductive organs or are less than 2 years post-menopausal
\. A negative serum pregnancy test prior to receiving the tracer
\. Willing to ensure that she or her partner uses effective contraception
during the trial and for 6 months thereafter

Exclusion Criteria

Medical or psychiatric conditions that compromise the patient's ability to give informed consent
History of infusion reactions to Bevacizumab or other monoclonal antibody therapies
Significant renal, cardiac, or pulmonary disease (ASA III-IV)
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