Last updated on December 2018

Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT)

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Alcohol abuse | Tuberculosis | HIV/AIDS
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  1. Age > 18 years old
  2. Patient of the MRRH ISS Clinic
  3. HIV-infected
  4. Consume alcohol (self-reported consumption in the prior 3 months) (2/3) OR prior year non-drinker (1/3)
  5. Live within 2 hours of travel time to the ISS Clinic
  6. Fluent in either Runyankole or English
  7. No ALT/AST elevations (< = 2X ULN) confirmed by testing
  8. On ART for at least 6 months
  9. No history of active TB, TB treatment, or TB preventive therapy
  10. No probable current active TB as determined by symptom screening and followed by chest X-ray and Xpert MTB/RIF (if symptomatic)
  11. Positive TST results confirmed by testing

Exclusion Criteria:

  1. Plans to move out of the catchment area within 6 months
  2. Probable TB via symptom screen and subsequent assessments
  3. History or current or past active TB, TB treatment, or TB preventive therapy
  4. ALT or AST >2x ULN
  5. Pregnant women

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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