Comparative Study Between the Effect of Diclofanic and Ketorolac in Post Tonsillectomy Pain Management

  • STATUS
    Not Recruiting
  • participants needed
    100
  • sponsor
    Assiut University
Updated on 24 January 2021
analgesics
analgesia
diclofenac
ketorolac

Summary

Compare between the analgesic efficacy of diclofenac sodium and ketorolac tromethamine in post-tonsillectomy pain management.and Compare between the effect of diclofenac sodium and ketorolac tromethamine on post-tonsillectomy bleeding

Description

patients will be randomly allocated to two groups of 50 patients each Group (A): will receive intra-operative diclofenac sodium at dose of 0.3 mg/kg intravenously.

Group (B): will receive intra-operative ketorolac tromethamine at dose of 0.5 mg/kg intravenously.

Then the two groups will continue postoperatively on the same drug received intra-operative

I. Intra-operative data:

Bleeding score will be assessed by the surgeon at the end of the operation using the following Scale for bleeding assessment (0 = no bleeding, 1 = bleeding as usual, 2 = bleeding more than usual, 3 = profuse, 4 = excessive, and lastly 5 = excessive and continuous).

II. Early Post-operative data:

  1. Post- tonsillectomy bleeding assessments;
    • Bleeding score will be recorded immediately postoperative and 3, 6, 12 and 24h postoperatively.
    • Hospital re-admission because of bleeding.
    • Re-operation because of bleeding.
  2. Post- tonsillectomy pain assessments; Pain intensity will be assessed postoperatively by the verbal rating scale (VRS; 0 = no pain, 1 = mild pain, 2 = moderate pain, 3= severe pain, and lastly 4= excruciating pain). VRS assessment will be performed immediately postoperative and 3, 6, 12 and 24h postoperatively. Analgesia will be given if requested or if the VRS2. Patients in Group A will receive diclofenac sodium 0.3 mg/kg iv, while patients in Group B will receive ketorolac tromethamine 0.5 mg/kg.

The total consumption of analgesics used in each group in the first 24 h postoperative will be calculated and the time of the first request for analgesia will be recorded.

  • Time to first oral intake.
  • Total intake of food in the 1st 24h postoperatively (solids vs. semisolids).

IV. Late Post-operative data:

As aweekly follow up for 2 weeks :

  1. bleeding tendency
  2. Dysphagia.
    • Time needed to restore normal dietary habits

Details
Condition Pain, Acute
Treatment ketorolac, Diclofenac
Clinical Study IdentifierNCT03178539
SponsorAssiut University
Last Modified on24 January 2021

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