VCRC Tissue Repository

  • STATUS
    Recruiting
  • End date
    Sep 2, 2022
  • participants needed
    1000
  • sponsor
    University of Pennsylvania
Updated on 2 April 2021
diagnostic tests
vasculitis
vascular disease
vascular diseases

Summary

The purpose of this study is to collect existing tissue specimens from subjects enrolled in Vasculitis Clinical Research Consortium (VCRC) studies. Analysis of these tissue specimens and linked clinical data collected through VCRC studies may lead to the identification and development of a series of translational research projects. Results of these studies will provide vasculitis researchers with insight into the causes of these diseases and generate new ideas for diagnostic tests and therapies, and will be of great interest to the larger communities of researchers investigating vasculitis and other autoimmune, inflammatory, and vascular diseases.

Description

Biopsy specimens collected as standard of care for these diseases will be retrieved and used in research. The most common biopsies performed are kidney, lung, skin, nerves, and vessels; however, other tissue is also of interest for the study. Biopsies are not performed as part of this protocol, rather we will request consent to collect biopsy specimens already collected under routine care.

Details
Condition Aortitis, Giant Cell Arteritis, Wegener's Granulomatosis, Polyarteritis Nodosa, Pulseless Disease, Churg-Strauss Syndrome, Microscopic Polyangiitis, Allergic Purpura, Eosinophilic Granulomatosis With Polyangiitis, Granulomatosis With Polyangiitis, IgA Vasculitis, Cutaneous Vasculitis, takayasu's arteritis, temporal arteritis
Clinical Study IdentifierNCT02967068
SponsorUniversity of Pennsylvania
Last Modified on2 April 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

A participant will be deemed eligible for this study if the participant is/was enrolled in another one of the VCRC observational/longitudinal protocols (5502, 5503, 5504, 5505, 5506, 5507, 5563) and/or one of the VCRC interventional studies (5522, 5523, 5526, 5527, or 5562)

Exclusion Criteria

Inability to give informed consent (or their guardians in the case of children) and to sign the consent form
Unwilling to allow the use of their tissue for research
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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