Last updated on September 2020

EROSION II: OCT Guided PPCI in STEMI


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: STEMI - ST Elevation Myocardial Infarction
  • Age: Between 18 - 75 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Men or non-pregnant women >18 years of age and < 75 years of age
  • Patients undergo cardiac catheterization for STEMI. STEMI will be defined as continuous chest pain for >30 minutes, arrival at the hospital within 24 hours from chest pain onset, ST-segment elevation >0.1 mV in at least two contiguous leads, or new left bundle-branch block on the 12-lead electrocardiogram (ECG), and elevated cardiac markers (troponin T/I or creatine kinase-MB).
  • Culprit lesion located in a native coronary artery
  • TIMI flow grade 3 and diameter stenosis < 70% on angiogram or MLA1.6mm2
  • Definite erosion and rupture defined by OCT
  • Patients able to provide written informed consent

Exclusion Criteria:

  • Left ventricular ejection fraction < 30%.
  • Lesions on LM, ostial LAD.
  • Long lesions, circuity lesion and angulation lesions
  • more than 2 severe lesions
  • Massive residual thrombosis after the thrombus aspiration.
  • With the history of cardiopulmonary resuscitation (CPR), acute pulmonary edema and cardiac shock on the attacks.
  • Life expectancy < 1 year.
  • Contraindication to the contrast media.
  • Creatinine level > 2.0 mg/dL or end-stage kidney disease.
  • Serious liver dysfunction.
  • Patients with hemodynamic or electrical instability (including shock).
  • Any contraindication against the use of ticagrelor.
  • Investigator considers the patient is not suitable.

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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