Last updated on April 2019

ASCT With Nivolumab in Patients With Multiple Myeloma


Brief description of study

This is an open-label, single center trial of Autologous Stem Cell Transplantation (ASCT) with nivolumab in multiple myeloma patients to determine the efficacy and safety of ASCT and PD1 inhibitor combination.

For this purpose, 30 multiple myeloma patients, who have received induction therapy and have achieved a partial response (PR), stable disease (SD) or progression, and thus have unfavorable prognosis, will be treated with nivolumab administered iv at a dose of 100 mg on days 3 before and 17 after high-dose melphalan with autologous stem cell transplantation.

Clinical Study Identifier: NCT03292263

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Boris V Afanasyev, MD, Prof.

Saint Petersburg, Russian Federation
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