Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours (HyBT-H&N)

  • STATUS
    Recruiting
  • End date
    Dec 31, 2027
  • participants needed
    96
  • sponsor
    University of Erlangen-Nürnberg Medical School
Updated on 25 February 2022

Summary

The aim of the present trial is to assess the prospective results of protocol-based interstitial pulsed-dose-rate (PDR) brachytherapy with interstitial hyperthermia (iHT) in a group of selected patients where salvage surgery with clear resection margins was not possible.

Details
Condition Locally Recurrent Head and Neck Cancer
Treatment brachytherapy, hyperthermia
Clinical Study IdentifierNCT03238378
SponsorUniversity of Erlangen-Nürnberg Medical School
Last Modified on25 February 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Histologically confirmed recurrent carcinoma of the head and neck region
Stage rcT1-3
Tumor anatomy and location suitable for brachytherapy techniques
cN0/pN0 or rpN+ & R0 with <3 pos. LND & without invasion of capsula
M0
ECOG 0-2
Previous radiation therapy up to at least 50 Gy
Previous radiation therapy completed more than 6 months ago
Written study-specific informed consent

Exclusion Criteria

cT4
rpN+ with >2 pos. LND or invasion of capsula
Pregnant or lactating women
Collagen vascular disease
The presence of congenital diseases with increased radiation sensitivity, for example Ataxia telangiectatica or similar
Psychiatric disorders
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note