Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension

  • STATUS
    Recruiting
  • participants needed
    50
  • sponsor
    Medical University of Vienna
Updated on 31 January 2023
hypertension
apnea
sleep disorder
sleep-disordered breathing
obstructive sleep apnea
central sleep apnea, cheyne-stokes breathing
riociguat
central sleep apnea

Summary

There is evidence for a high prevalence of Sleep Disorder Breathing (SDB) in patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH). Central Sleep Apnea, Cheyne-Stokes Breathing and Obstructive Sleep Apnea appear to occur in CTEPH. However, there is no information on the impact of CTEPH treatment modalities on concomitant SDB. Furthermore, the use of PAP therapy in CTEPH has not yet been investigated. CTEPH is a rare and serious disease and there may be a bidirectional association of SDB and CTEPH.

This study plans to investigate the prevalence of SDB in CTEPH and compare it to datasets of large epidemiological studies on SDB. Furthermore, the impact of CTEPH treatment on SDB will be analyzed and CTEPH patients for possible PAP treatment will be defined.

Details
Condition Chronic Thromboembolic Pulmonary Hypertension, Sleep Disordered Breathing
Treatment Riociguat, Pulmonary Endarteriectomy, Ballon Pulmonary Angioplasty
Clinical Study IdentifierNCT03074539
SponsorMedical University of Vienna
Last Modified on31 January 2023

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