Green Tea Extract for Endometriosis Treatment

  • End date
    Dec 4, 2022
  • participants needed
  • sponsor
    Chinese University of Hong Kong
Updated on 25 February 2022
pelvic pain


The purpose of the study is to evaluate the efficacy and safety of green tea in endometriosis.


Women with endometrioma will be randomised into either the experimental group or the placebo comparator group in a 1:1 ratio. The subjects will be given SUNPHENON EGCg or placebo for 3 months prior to their planned surgery.

Condition Endometriosis
Treatment Placebo, SUNPHENON EGCg
Clinical Study IdentifierNCT02832271
SponsorChinese University of Hong Kong
Last Modified on25 February 2022


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Inclusion Criteria

Complaints of pelvic pain, dysmenorrhoea and/or dyspareunia 6 months; and
Verbal pain rating scale > 4/10 and visual analogue pain scale > 4cm; and
Ultrasound confirmed endometrioma with or without fibroid and adenomyoma; and
Planned surgery treatment within 4-6 months

Exclusion Criteria

Age < 20 years beyond or >40 year behind the active reproductive age; or
BMI <18.5 kg/m2 as underweight or >25 kg/m2 as overweight; or
Chronic pelvic pain or low back pain due to other medical conditions, e.g. urological disorders and orthopaedic disorders; or
Secondary dysmenorrhoea due to gynaecological conditions other than endometriosis, e.g. pelvic inflammatory diseases, genitourinary infections, gynaecological tumours, etc.; or
Primary dysmenorrhoea without any underlying disease identified; or
Ultrasound suggested polycystic ovary, haemorrhagic ovarian cyst, ovarian dermoid cyst, cystic neoplasm, tubo-ovarian abscess or other ovarian pathologies in the same ovary; or
Chronic medical conditions under long-term medications; or
Endometriosis under active medication in past 1 month; or
History of herbal medicine intake in past 1 month
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