Dapagliflozin in PRESERVED Ejection Fraction Heart Failure

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    Saint Luke's Health System
Updated on 22 September 2021


The primary purpose of this study is to evaluate the impact of dapagliflozin, as compared with placebo, on heart failure, disease specific biomarkers, symptoms, health status and quality of life in patients with chronic heart failure with preserved systolic function.


A 12-week randomized, double-blind, placebo-controlled trial to evaluate the effects of once-daily dapagliflozin 10 mg on heart failure disease-specific biomarkers (NTproBNP and BNP), symptoms, health status, and quality of life in patients with chronic heart failure with preserved systolic function. An imaging substudy will also be conducted to explore the effects of dapagliflozin vs. placebo on various echocardiographic parameters.

Condition Chronic Heart Failure With Preserved Systolic Function
Treatment Dapagliflozin matching placebo, Dapagliflozin 10Mg Oral Tablet
Clinical Study IdentifierNCT03030235
SponsorSaint Luke's Health System
Last Modified on22 September 2021

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