Last updated on March 2019

Management of Low-risk DCIS


Brief description of study

A substantial number of DCIS lesions will never form a health hazard, particularly if it concerns slow-growing low-grade DCIS. This implies that many women might be unnecessarily going through intensive treatment resulting in a decrease in quality of life and an increase in health care costs, without any survival benefit.

The LORD (LOw Risk DCIS) study is a randomized, international, multicenter, phase III non-inferiority trial, and aims to determine whether screen-detected low-grade DCIS can safely be managed by an active surveillance strategy or that the conventional treatment, being either WLE alone, WLE + RT, or mastectomy, and possibly HT, should remain the standard of care.

Clinical Study Identifier: NCT02492607

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Catharina Ziekenhuis

Eindhoven, Netherlands
6.2miles
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Maxima Medisch Centrum

Eindhoven, Netherlands
6.2miles
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