Study of Letrozole in Recurrent Gliomas

  • STATUS
    Recruiting
  • End date
    Jun 22, 2023
  • participants needed
    42
  • sponsor
    University of Cincinnati
Updated on 22 September 2021

Summary

The purpose of this study is to determine the ability of letrozole to penetrate the blood brain barrier and concentrate in gliomas.

Description

Nine to forty-two (42 patients only if every cohort required expansion) total patients are planned for this phase 0/1 study to explore the ability of letrozole to penetrate the blood brain barrier and gliomas.

Details
Condition Malignant neoplasm of brain, Brain Tumor (Pediatric), Brain Cancer, Brain Tumor, brain tumors
Treatment Letrozole Oral Tablet
Clinical Study IdentifierNCT03122197
SponsorUniversity of Cincinnati
Last Modified on22 September 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Recurrent brain glioma with plan for resection or biopsy
ECOG 0-2
Adequate labs

Exclusion Criteria

Receiving other investigational agents
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note