Extracorporal Shock Wave Treatment to Improve Nerve Regeneration

  • participants needed
  • sponsor
    Ludwig Boltzmann Gesellschaft
Updated on 25 July 2021


This study evaluates the impact of extracorporeal shock wave treatment after microsurgical coaptation of finger nerves. Participants will be randomized into two treatment groups with different settings and a sham group. The participants will thereafter followed-up in a prospective, double-blind study design.


Extracorporeal shock wave treatment is CE certified in Austria, Europe and licensed for indications like achillodynia, epicondylitis, or tendinitis calcanea. The Orthogold 100 device by MTS Medical UG will be used for this study.

Defocused low-energy extracorporeal shock wave therapy (ESWT) has gained acceptance as a therapeutic tool in different medical settings. It has been shown, that shock waves stimulate of the metabolic activity of different cell type, including osteoblasts, tenocytes, endothelial cells and chondrocytes. Furthermore, it has proved effective in clinical applications relating to bone and wound healing and myocardial ischaemia. Until now, no studies have been performed regarding the effects of ESWT on regeneration of peripheral nerve injuries in humans.

Condition Peripheral Neuropathy, Peripheral Nerve Injury
Treatment SHAM, MTS Medical UG Orthogold 100
Clinical Study IdentifierNCT03147313
SponsorLudwig Boltzmann Gesellschaft
Last Modified on25 July 2021

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