Last updated on July 2020

EUS - Guided Choledocho-duodenostomy Versus ERCP With Covered Metallic Stents in Patients With Unresectable Malignant Distal Common Bile Duct Strictures

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Malignant Biliary Obstruction
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Age 18 years old with informed consent
  • Histologically (preferred) or radiologically confirmed distal malignant bile duct tumors
  • Inoperability by staging, comorbidities or patient wishes
  • Distal tumors 2cm away from the portal hilum
  • Bilirubin > 50umol/L at diagnosis

Exclusion Criteria:

  • Multiple hepatic metastases with significant blockage of one or more liver segments (if no segment blockage, metastasis is not an exclusion criteria)
  • Presence of main portal vein thrombosis
  • Prior SEMS placement
  • Intraductal papillary mucinous carcinomas
  • Prior Billroth II or roux-en Y reconstruction
  • History of bleeding disorder or use of anticoagulation
  • Child's B/C cirrhosis
  • Pregnancy
  • Performance status ECOG 3 (confined to bed / chair > 50% waking hours)
  • Presence of other malignancy
  • Life expectancy < 3months

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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