Sublobar Resection Versus Lobectomy for cT1N0M0 Non-small-cell Lung Cancer

  • End date
    Dec 31, 2023
  • participants needed
  • sponsor
    Shanghai Zhongshan Hospital
Updated on 24 February 2022
lung carcinoma


The incidence rate of ground-glass opacity (GGO) has been increasing these years. A great number of retrospective studies suggested that sublobar resection was better for some GGO patients. However, no prospective clinical study supports the perspective. This study is prospective, multi-center, randomized-controlled. The aim of this study is to investigate whether sublobar resection is inferior to lobectomy for cT1N0M0 non-small-cell lung cancer or not.

Condition Carcinoma, Non-Small-Cell Lung
Treatment lobectomy, Sublobar resection
Clinical Study IdentifierNCT03108560
SponsorShanghai Zhongshan Hospital
Last Modified on24 February 2022


Yes No Not Sure

Inclusion Criteria

cT1N0M0 non-small-cell lung cancer
ground-glass opacity, 2cm, GGO25%
eligible for both lobectomy and sublobar resection
intraoperative pathology is minimally-invasive adenocarcinoma or invasive adenocarcinoma
intraoperative pathology of biopsied station 10 lymph node is negative

Exclusion Criteria

intraoperative pathology is benign nodule, atypical adenomatous hyperplasia, or adenocarcinoma in-situ
intraoperative pathology of biopsied station 10 lymph node is positive
multiple GGOs, lesions other than dominant lesion are malignant or >5mm
history of thoracic surgery
history of malignancy in recent 5 years
unstable systemic disease
patients with psychiatric disorders
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact



Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note