Last updated on February 2018

Vaginal and Urinary Microbiome Trial


Brief description of study

A randomized controlled trial looking at the effects of vaginal estrogen and a nonhormonal alternative on the vaginal and urinary microbiome in women with genitourinary syndrome of menopause.

Detailed Study Description

This is a study is looking at the effects of vaginal estrogen and a nonhormonal alternative on the vaginal and urinary microbiome in women with genitourinary syndrome of menopause with the primary objective is to describe the bacterial communities associated in the vagina and urine of postmenopausal women receiving treatment for genitourinary syndrome of menopause with Premarin vaginal cream and a nonhormonal alternative, such as, apricot kernel oil. The participants will be randomized to either Premarin vaginal cream or apricot kernel oil. They will be given validated questionnaires to assess their urinary and vaginal symptoms, sexual function, quality of life, and impressions of severity and improvement.

Clinical Study Identifier: NCT02869165

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Recruitment Status: Open


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