Last updated on February 2018

Tzanck Smear With Methylene Blue Stain for Herpes

Brief description of study

To compare the sensitivity of Tzanck smear with methylene blue stain versus traditional Giemsa stain in patients with herpes infection.

Detailed Study Description

A smear from the lesional skin of the patients suspected having Herpes simplex, Herpes zoster and Varicella zoster skin infections will be collected (in a clinical routine setting). The specimen will be stained with methylene blue in addition to the Giemsa stain. Polymerase chain reaction study for herpes antigen will be performed in some of the specimens. The sensitivity, specificity, positive predictive value and negative predictive value will be calculated from the results of the study.

Clinical Study Identifier: NCT03178747

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Pawinee Rerknimitr, MD, MSc

Division of Dermatology, Faculty of Medicine, Chulalongkorn University
Bangkok, Thailand
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Recruitment Status: Open

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