Last updated on January 2019

Coronary Microcirculatory and Bioresorbable Vascular Scaffolds

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Angina | Coronary Artery Disease | Ischemic Heart Disease | Stable | Coronary heart disease
  • Age: Between 18 - 75 Years
  • Gender: Male or Female

Inclusion Criteria:

  1. Patient age >18 years, <75 years.
  2. Lesion suitability for BVS deployment: target vessel calibre >2.3mm and <3.8mm reference diameter, without significant tortuosity or calcification.
  3. Listed for single-vessel PCI procedure.
  4. Lesion length28mm (to accommodate single BVS/DES)
  5. Preserved left ventricular ejection fraction (EF50%).

Exclusion Criteria:

  1. Patients with confirmed myocardial infarction within the preceding 2 months.
  2. Allergy or intolerance to aspirin, clopidogrel, prasugrel or ticagrelor or contraindication to 12 months' dual antiplatelet therapy.
  3. Contraindication to use of adenosine (asthma/chronic lung disease with documented bronchoreactivity).
  4. Significant known comorbidity or terminal condition with life expectancy <6 months.
  5. Pregnancy.
  6. Coagulopathy or warfarin treatment.
  7. Significant renal impairment (baseline creatinine>130 mmol/l).
  8. Other comorbid condition that may affect microcirculatory function or troponin release (eg. Seropositive inflammatory conditions).
  9. Inability to comply with follow-up requirements.
  10. Target lesion in left mainstem, saphenous vein or arterial grafts.
  11. Chronic total occlusion.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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