Effectiveness of Unilateral Versus Bilateral Intensive Training in Children With Cerebral Palsy

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    National Taiwan University Hospital
Updated on 22 March 2022
botulinum toxin
botulinum toxin type a


This 3-year research project aims to investigate and compare the immediate and long-term treatment effectiveness as well as motor improving curve and potential predictors of the unimanual intensive training and bimanual intensive training protocols with an equivalent intervention period in children with hemiplegic CP and children with CP with apparently one side affected. In addition, based on the ICF-CY model, comprehensive outcome measures including motor functions as well as psychological functions will be included.

Condition Cerebral Palsy
Treatment unilateral upper limbs intensive training, bilateral upper limbs intensive training
Clinical Study IdentifierNCT02808156
SponsorNational Taiwan University Hospital
Last Modified on22 March 2022


Yes No Not Sure

Inclusion Criteria

aged between 3 and 16 years
diagnosed with congenital hemiplegic or children with CP with one more affected side; (3) apparently disuse phenomenon of the more affected hand at spontaneous contexts
Participants will be exclude for
excessive muscle tone (Modified Ashworth Scale ≤ 2 at any joints of the upper limb) before beginning treatment (Bohannon & Smith, 1987)
severe cognitive, visual, or auditory disorders according to medical documents, parental reports, and the examiner's clinical observation
injections of botulinum toxin type A or operations on the UE within 6 months
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