Fludarabine and Cytarabine Versus High-dose Cytarabine for CBF-AML
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- STATUS
- Recruiting
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- End date
- Jul 29, 2024
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- participants needed
- 200
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- sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Summary
The purpose of the study is to determine whether Fludarabine in combination with cytarabine is more effective than high-dose cytarabine in post-remission therapy for patients with core-binding factor acute myeloid leukemia
Description
The recurrence rate, relapse-free survival rate, and overall survival rate of CBF-AML patients were compared between FA and HIDAC regimens. Observe the prognostic value of factors such as c-KIT gene mutation and minimal residual disease (MRD).
Details
| Condition | Acute Myeloid Leukemia, Core-Binding Factor |
|---|---|
| Treatment | cytarabine, Fludarabine |
| Clinical Study Identifier | NCT02926586 |
| Sponsor | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine |
| Last Modified on | 29 May 2022 |
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