Serial, Non-invasive Analysis of Exhaled Breath Condensate in Ventilated Trauma Patients
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- STATUS
- Recruiting
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- End date
- Dec 17, 2022
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- participants needed
- 350
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- sponsor
- Vanderbilt University Medical Center
Summary
To determine if the analysis of exhaled breath condensate correlates with the development & resolution of pneumonia.
Description
This proposal investigates the utility of exhaled breath condensate fluid (EBCF) collected from heat moisture exchange (HME) filters connected to patient's endotracheal tubes for early, non-invasive detection of ventilator-associated pneumonia (VAP) in critically ill or injured ICU patients. The development of pneumonia during mechanical ventilation is the most common healthcare-associated infection in severely injured patients, accounting for substantial morbidity, excess ICU and hospital stay, additional cost and increased mortality.
Details
| Condition | Ventilator Associated Pneumonia (VAP) |
|---|---|
| Treatment | molecular analysis of exhaled breath condensate, molecular analysis of mini-bronchoalveolar lavage (BAL) aspirate, molecular analysis of bronchoalveolar lavage (BAL) aspirate |
| Clinical Study Identifier | NCT02652247 |
| Sponsor | Vanderbilt University Medical Center |
| Last Modified on | 24 February 2022 |
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