Last updated on February 2018

Role of Geriatric Intervention in Treatment of Older Patients With Cancer (PREPARE)


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Malignant neoplasm of prostate | Lung Neoplasm | bladder cancer | Ovarian Cancer | Bronchial Neoplasm | Lymphoma | Breast Cancer | Colorectal Cancer
  • Age: Between 70 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  1. Patient older 70 years and older
  2. Performance status 0 to 3 (WHO)
  3. G8 and QLQ-C30 questionnaires 'score are available
  4. No previous geriatric evaluation during cancer treatment
  5. Locally advanced or metastatic disease :
  6. 1st line medical treatment :
    • Breast cancer : locally advanced or metastatic disease, hormone-resistant and Her2 negative,
    • Colon and rectum : metastatic (unresectable metastasis),
    • Prostate cancer : metastatic and refractory to hormonal castration,
    • Bladder cancer : locally advanced or metastatic,
    • Ovarian cancer : advanced stage (IIb to IV),
    • Lung cancer : metastatic non-small cell,
    • Lymphomas (indolent and aggressive)
  7. Or 2nd line medical treatment :
    • Breast cancer : locally advanced or metastatic disease, hormone-resistant and Her2 negative,
    • Colon and rectum : metastatic (unresectable metastasis),
    • Prostate cancer : metastatic and refractory to hormonal castration,
    • Ovarian cancer : advanced stage (IIb to IV),
    • Lymphomas (indolent and aggressive)
  8. Life expectancy over 6 months
  9. Signed informed consent
  10. Patients with a French social security in compliance with the French law relating to biomedical research (Article L.1121-11 of French Public Health Code).

Exclusion Criteria:

  1. Patient who already received 2 medical treatment lines
  2. Exclusive 1st or 2nd treatment lines of :
    • Hormonotherapy (except for prostate cancer : abiteratone acetate is allowed),
    • Surgery,
    • Radiotherapy,
  3. "Best supportive care" treatment
  4. Patient unable to understand quality of life questionnaire
  5. Patient unable to follow and comply with the study procedures because of any geographical, social or psychological reasons.
  6. Patient placed under guardianship
  7. Planned concomitant participation to another medical interventional trial during the 12 months following the inclusion in the randomized study PREPARE
  8. Previous enrolment in the present study

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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