Last updated on May 2018

Remote Ischemic Preconditioning as a Method Against Subclinical Renal Injury and Contrast-induced Nephropathy


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Stable Angina | peripheral arterial disease | Atherosclerosis | Contrast Induced Nephropathy
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Age greater than 18 years, no upper age limit
  • Patients with stable coronary artery disease (II - III class according to the Canadian Cardiovascular Society) hospitalized for coronarography or with lower extremity arterial disease hospitalized for angiography
  • Written informed consent

Exclusion Criteria:

  • Pregnancy
  • Age less than 18 years
  • eGFR < 30 ml/min/1,73 m2
  • Simultaneous participation in an other clinical trial
  • Coexisting pathology of the upper-limbs limiting the use of the cuff (bilateral amputee, recent trauma, chronic ulcers, significant upper limb peripheral atherosclerosis (radial pulse not palpable on either side))
  • Malignant tumor (in remission less than 5 years or ongoing treatment)
  • Documented allergic reaction to iodinated contrast agent
  • Acute infection (body temperature 38 degrees Celsius or higher, c reactive protein 50mg/L or higher)
  • Cardiac rhythm abnormalities (atrial fibrillation, frequent supraventricular premature complexes)
  • Documented myocardial infarction within 30 days
  • Inability to understand the instructions of the study
  • Vascular surgery in axillary region
  • Unable to lie supine for 40 minutes
  • Home oxygen treatment
  • Documented upper limb deep vein thrombosis

Recruitment Status: Closed


Brief Description Eligibility Contact Research Team


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