Last updated on April 2018

Efficacy of Omega-3 as Adjunctive Therapy for Medically Intractable Epilepsy: A Prospective Open-label Pilot Study

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Epilepsy
  • Age: Between 20 - 70 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Patients with medically intractable, focal or generalized, epilepsy: Patients with localization-related partial onset or generalized tonic/clonic seizure according to the International League Against Epilepsy (ILAE) can be included. Medically intractable epilepsy means that recurrent seizures occur even though two or more anti-epileptic drugs have been used appropriately for over one year.
  • Seizure frequency criteria: three seizures per one month for recent 3 months before enrollment
  • Seizure criteria: simple partial, complex partial, or tonic-clonic seizures
  • Subjects with normal cognitive function: patients who can perform normal daily life. If not definite, enrollment will be done with K-MMSE score over 27.

Exclusion Criteria:

  • Poor general medical condition: comorbid with heart, lung, liver diseases
  • Patients who have history of pseudo-seizure
  • Anti-epileptic drugs has been changed in recent one month.
  • Chronic alcoholic
  • Seizure count cannot be done since seizures occur successively.
  • Allergy to fish
  • High risk of bleeding such as trauma or operation
  • Liver function abnormality
  • Pregnant or lactating women, or women who plans to have children
  • Patients who have participated in the other clinical trial in recent one month

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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