Last updated on July 2019
Intranasal Ketamine for Anxiolysis in Pediatric Emergency Department Patients
Are you eligible to participate in this study?
You may be eligible for this study if you meet the following criteria:
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Conditions: childhood ALL | Anxiety | ANXIETY NEUROSIS | Procedural Anxiety
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Age: Between 2 - 12 Years
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Gender: Male or Female
Inclusion Criteria:
- Patients age 2 to 12 years who present to the ED
- Requiring intravenous access
- Requiring laceration repairs
- Requiring incision and drainage of abscesses
- Requiring digital nerve blocks
- Requiring radiological imaging
- Requiring bladder catheterization
- Requiring foreign body removal.
Exclusion Criteria:
- Vital sign abnormalities greater than 20% deviation from age-normalized ranges
- Altered mental status/delirium or intoxication
- Patient or patient's parent/guardian are unwilling to participate or provide informed consent
- Any allergy to ketamine or midazolam
- Patient is female with history of menarche
- Presence of chronic oxygen-dependent pulmonary disease, liver cirrhosis, or renal disease requiring dialysis
- Presence of ischemic heart disease, heart failure, or a history of unstable dysrhythmias
- Presence of intracranial mass or vascular lesion.
- Presence of a history of psychosis or hallucinations
- Weight greater than 100kg
- History of increased intracranial pressure/ hypertensive hydrocephalus within the last 3 months
- Non-English speaking/reading parent/guardian and/or patients
- Patient is acutely psychotic
- Provider feels that patient currently or likely will require chemical and/or physical restraints
- History of prolonged QT-interval
- Nasal trauma
- Epistaxis
