Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material

  • STATUS
    Recruiting
  • days left to enroll
    25
  • participants needed
    30
  • sponsor
    University of California, Los Angeles
Updated on 26 January 2021
root canal therapy
root canal filling

Summary

Non-surgical root canal therapy (RCT) represents a standard of treatment that addresses infected pulp tissue in teeth and protects against future infection while preserving the tooth for the patient for mainly cosmetic purposes. RCT is offered as the better cosmetic, cheaper, and less time intensive treatment option for a patient compared to those of dental implantation. Dental implantation is the alternative to RCT, and they are both originally offered at the time of the initial consultation. RCT involves non-surgically removing dental pulp comprising blood vessels and nerve tissue, decontaminating residually infected tissue, and using a filler material to replace the non-surgically created space where the pulp was removed. Currently, standard of care treatment for RCT utilizes gutta-percha as the root canal filling material. Our research group has previously demonstrated NDGP's improvement in tensile strength compared to those of gutta-percha. This research studies a new type of filler, gutta-percha modified by the addition of nanodiamond material (NDGP). This is an equivalence study of NDGP and standard gutta-percha administration.

Details
Condition Pulp Necrosis, Dental pulp disorder, Nerve Root Pain Nec, endodontic disease
Treatment Nanodiamond reinforced Gutta Percha, Gutta Percha, Gutta Percha
Clinical Study IdentifierNCT02698163
SponsorUniversity of California, Los Angeles
Last Modified on26 January 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

years old or older when patient is referred to UCLA endodontics department for root canal therapy
Patient referral to UCLA endodontics department for root canal therapy

Exclusion Criteria

preoperative periodontal disease
prior non-surgical and surgical endodontic treatment
currently taking medications used to treat osteoporosis or any form of IV biphosphonates
allergic to dental materials
dental phobia
MD consult/medically compromised/prophylaxis needed
developmental/congenital disorders
craniofacial disorder/syndromic cases
low pain tolerance ascertained from past dental experience
current moderate to severe periodontitis
previous RCT/initiated pulp therapy
previous apical surgery
previous surgical root canal procedure
with psychiatric and/or mental health history
poor oral hygiene
poor diet
illicit and/or recreational drug use
complicated dental history
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