Last updated on May 2018

Right Heart Dysfunction and Pulmonary Hypertension Evaluation in Airway Disease Using Cardiac Magnetic Resonance


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Chronic Obstructive Lung Disease | Asthma
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

Airway Disease (Asthma and COPD)

  1. Participant is willing and able to give informed consent for participation in the study.
  2. Male or Female, aged 18 years or above.
  3. Participants diagnosed with Asthma or COPD with airflow limitation (FEV1% predicted < 80%) with no exacerbations for at least 4 weeks prior to study entry.
  4. Participant has no clinical contraindication for CMR scan.
  5. Able (in the Investigators opinion) and willing to comply with all study requirements.
  6. Willing to allow his or her General Practitioner and consultant, if appropriate, to be notified of participation in the study.

Healthy Volunteers

  1. Participant is willing and able to give informed consent for participation in the study.
  2. Male or Female, aged 18 years or above.
  3. Healthy participant in good health with no past history of cardiovascular or respiratory disease.
  4. Participant has no clinical contraindication for CMR scan.
  5. Able (in the Investigators opinion) and willing to comply with all study requirements.
  6. Willing to allow his or her General Practitioner and consultant, if appropriate, to be notified of participation in the study.

Exclusion Criteria:

Airway Disease (Asthma and COPD)

The participant may not enter the study if ANY of the following apply:

  1. Female participants who are pregnant, lactating or planning pregnancy during the course of the study.
  2. Severe renal impairment eGFR < 30 ml/min.
  3. Contraindication for undergoing CMR scan including permanent pacemaker and surgical procedure within last 6 weeks.
  4. Unable to understand / read English
  5. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study.

Healthy Volunteers

The participant may not enter the study if ANY of the following apply:

  1. Female participants who are pregnant, lactating or planning pregnancy during the course of the study.
  2. Severe renal impairment eGFR < 30 ml/min.
  3. Contraindication for undergoing CMR scan including permanent pacemaker and surgical procedure within last 6 weeks.
  4. Unable to understand / read English
  5. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study.

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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