Last updated on February 2018

Nicotinamide Adenine Dinucleotide and Skeletal Muscle Metabolic Phenotype

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Senility
  • Age: Between 70 - 80 Years
  • Gender: Male

Inclusion Criteria:

  • Male sex
  • Age 70-80 years
  • BMI 20-30kg/m2
  • Participants who are able to discontinue aspirin for 3 days prior to the muscle biopsy
  • Participants who are able to discontinue statins and vitamin D supplements for a week before the second visit and for the duration of the study

Exclusion Criteria:

  • Serious active medical conditions including inflammatory diseases or malignancies
  • Significant past medical history including diabetes mellitus, ischaemic heart disease, cerebrovascular disease, significant respiratory disease requiring medication, epilepsy
  • High blood pressure (BP>160/100mmHg)
  • Oral Anticoagulants (like Warfarin, Dabigatran, Rivaroxaban) or Clopidogrel therapy which will increase the risk of bruising following a muscle biopsy

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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