CPAP to Improve Swallow Function Post Total Laryngectomy

  • STATUS
    Recruiting
  • End date
    Dec 26, 2023
  • participants needed
    10
  • sponsor
    University of California, Davis
Updated on 26 March 2022

Summary

Investigator initiated prospective study to determine whether use of Continuous Positive Airway Pressure (CPAP) can improve the swallow function in patients who underwent total laryngectomy and are experiencing difficulty swallowing

Description

Total laryngectomy is a procedure that involves surgical removal of the larynx and separation of the digestive and airway tracts. The procedure is typically conducted for cases of laryngeal cancer and intractable aspiration. Following this procedure, patients are no longer at risk for aspiration; however some patients continue to experience difficulties in propulsion of food or drink throughout the pharynx. Previous research has demonstrated a reduction in pharyngeal contractile pressure and increased pharyngeal transit time in patients post laryngectomy. Continuous Positive Airway Pressure (CPAP) may assist bolus propulsion in these patients by increasing pressure in the direction of bolus flow. This study aims to evaluate the utility of a CPAP mask to improve pharyngeal swallow outcomes during Video Fluoroscopic Swallowing Exam (VFSE) in patients with dysphagia following total laryngectomy. This specific population could be well-suited for this application, since the digestive tract and airway are completely separate and there is no risk of the aspiration into the airway.

Details
Condition Oropharyngeal Dysphagia, Laryngectomy; Status
Treatment Continuous positive airway pressure
Clinical Study IdentifierNCT03328702
SponsorUniversity of California, Davis
Last Modified on26 March 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients at least 2 months after total laryngectomy
Undergoing Video Fluoroscopic Swallowing Examination

Exclusion Criteria

Patients with 100% neopharyngeal stenosis
Patients with active cancer within 2 months of the study
Patients with pharyngocutaneous fistula
Vulnerable population: Adults unable to consent, Pregnant women, and Prisoners
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