The Study About the Efficacy of Oral Limaprost After Surgery for Cervical Myelopathy

  • End date
    Dec 31, 2023
  • participants needed
  • sponsor
    Seoul National University Hospital
Updated on 12 May 2022


The limaprost alfadex can improve the surgical outcomes in patients with cervical myelopathy.

Condition Cervical Myelopathy
Treatment Placebo, Limaprost
Clinical Study IdentifierNCT02125981
SponsorSeoul National University Hospital
Last Modified on12 May 2022


Yes No Not Sure

Inclusion Criteria

Older than 20 years old
Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
Plan to undergo cervical surgery for myelopathy
JOA score less than 15 points
Signed informed consent of patient or legal guardian

Exclusion Criteria

Infection or malignancy
Taking Limaprost before surgery
Pregnancy or expected to be pregnant or breast feeding
severe cardiovascular, pulmonary, renal disease or distress, brain pathology
any related coagulopathy
any drug to cause bleeding tendency
severe pain from other disease
any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study
patient cannot follow study protocol, for any reason
Clear my responses

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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