Last updated on October 2018

Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Vasovagal syncope
  • Age: Between 40 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  1. 1 syncopal spells in the year preceding enrollment,
  2. -2 points on the Calgary Syncope Symptom Score for Structurally Normal Hearts, and (C) Age 40 years.

Exclusion Criteria:

  1. resting heart rate <50 bpm or supine systolic blood pressure <90 mm Hg in the absence of beta blockers or antihypertensive medications,
  2. other causes of syncope, such as sick sinus syndrome, ventricular tachycardia, complete heart block, postural hypotension or hypersensitive carotid sinus syndrome,
  3. an inability to give informed consent,
  4. important valvular, coronary, myocardial or conduction abnormality,
  5. hypertrophic cardiomyopathy or known or probable genetic arrhythmia
  6. a contraindication to beta blockers such as asthma, insulin-dependent diabetes, severe depression, peripheral vascular disease, chronic obstructive pulmonary disease, or previous intolerance of beta blockers,
  7. another clinical need for beta blockers which can not be met with other drugs,
  8. a seizure disorder,
  9. major chronic non-cardiovascular disease,
  10. an implanted defibrillator,
  11. Known hypersensitivity to metoprolol and derivatives.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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