Last updated on June 2019

Pre-hospital Anti-fibrinolytics for Traumatic Coagulopathy and Haemorrhage (The PATCH Study)


Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Acute Coagulopathy | Trauma
  • Age: Between 18 - 100 Years
  • Gender: Male or Female

Inclusion Criteria:

  • Adult patients (estimated age 18 years or older)
  • Injured through any mechanism
  • Coagulopathy of severe trauma (COAST) score of 3 points or greater
  • First dose of study drug can be administered within three hours of injury
  • Patients to be transported to a participating trauma centre

COAST score

  • Entrapment (ie in vehicle) [Yes = 1, No = 0]
  • Systolic blood pressure [<90 mmHg = 2, <100 mmHg = 1, 100 mmHg = 0]
  • Temperature [<32 =2, <35 = 1, 35 = 0]
  • Major chest injury likely to require intervention (e.g. decompression, chest tube) [Yes = 1, No = 0]
  • Likely intra-abdominal or pelvic injury [Yes = 1, No = 0]

Exclusion Criteria:

  • Suspected pregnancy
  • Nursing home residents

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


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