Global Strain and Mechanical Dispersion May Predict Death and Ventricular Arrhythmias Better Than Ejection Fraction

  • End date
    Dec 25, 2021
  • participants needed
  • sponsor
    Oslo University Hospital
Updated on 25 January 2021
Josef Marek
Primary Contact
Vseobecna fakultni nemocnice Praha/ Prague General hospital (1.2 mi away) Contact
+10 other location


The aim of the study is to investigate if global strain and mechanical dispersion may predict death and ventricular arrhythmias better than ejection fraction(EF) in patients with myocardial infarction and heart failure regardless of cause.


  1. The main aim of this study is to investigate if global strain and mechanical dispersion may predict death and ventricular arrhythmias better than left ventricular ejection fraction in patients with myocardial infarction and heart failure.
  2. In patients who receive internal cardioverter defibrillator(ICD) the main aim is to investigate if mechanical dispersion may predict ventricular arrhythmias better than EF.
  3. No interventions,only evaluation of the measurements obtained with transthoracic echocardiography.
  4. Follow up for 3 years

Condition Left Ventricular Function Systolic Dysfunction
Clinical Study IdentifierNCT02286908
SponsorOslo University Hospital
Last Modified on25 January 2021


Yes No Not Sure

Inclusion Criteria

All patients with
myocardial infarction
heart failure( defined as heart failure symptoms: reduced left ventricular function/ and or heart failure signs on chest x ray
planned for primary prophylactic ICD
over 18 years of age
Informed consent

Exclusion Criteria

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