Last updated on July 2018

S1314 Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer


Brief description of study

The primary focus of this study is to see if looking at tumor biomarkers using a program called coexpression extrapolation or "COXEN" may predict a patient's response to chemotherapy before surgery.

Detailed Study Description

The COXEN program will not select a patient's therapy, but the type of chemotherapy that he/she will receive will be randomly decided. The patient's response to chemotherapy will be used to test the usefulness of the COXEN program, which is the main goal of this trial. Other potential tests to predict a patient's response to chemotherapy will also be evaluated. In this study, the patient may receive the treatment in Arm 1 (gemcitabine and cisplatin) or the treatment in Arm 2 [methotrexate, vinblastine, doxorubicin, cisplatin, and filgrastim (or pegfilgrastim)]. There will be about 184 people taking part in this study (92 in each arm).

Clinical Study Identifier: NCT02177695

Contact Investigators or Research Sites near you

Start Over

Nicki Trevino

Michigan Cancer Specialists
Roseville, MI United States
  Connect »

Tareq Al Baghdadi

Great Lakes Cancer Management Specialists-Macomb Professional Building
Warren, MI United States
3.06miles
  Connect »

Tareq Al Baghdadi

Macomb Hematology Oncology PC
Warren, MI United States
3.06miles
  Connect »

Tareq Al Baghdadi

Michigan Breast Specialists-Warren
Warren, MI United States
3.06miles
  Connect »

Tareq Al Baghdadi

Saint John Macomb-Oakland Hospital
Warren, MI United States
3.06miles
  Connect »

Tareq Al Baghdadi

Bhadresh Nayak MD PC-Sterling Heights
Sterling Heights, MI United States
5.05miles
  Connect »

Nicki Trevino

Premier Hematology Oncology Care
Sterling Heights, MI United States
5.05miles
  Connect »

Tareq Al Baghdadi

Saint John Hospital and Medical Center
Detroit, MI United States
5.61miles
  Connect »

Tareq Al Baghdadi

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Grosse Pointe Woods, MI United States
5.61miles
  Connect »

Tareq Al Baghdadi

Lymphoma Clinic of Michigan
Grosse Pointe Woods, MI United States
5.61miles
  Connect »

Tareq Al Baghdadi

Michigan Breast Specialists-Grosse Pointe Woods
Grosse Pointe Woods, MI United States
5.61miles
  Connect »

Robert A. Chapman

Henry Ford Macomb Hospital-Clinton Township
Clinton Township, MI United States
8.18miles
  Connect »

Nicki Trevino

William Beaumont Hospital-Grosse Point
Grosse Pointe, MI United States
8.23miles
  Connect »

Nicki Trevino

Mitchell Folbe MD PC
Sterling Heights, MI United States
8.97miles
  Connect »

Tareq Al Baghdadi

Hematology Oncology Associates East PC
Macomb, MI United States
9.94miles
  Connect »

Tareq Al Baghdadi

Michigan Breast Specialists-Macomb Township
Macomb, MI United States
9.94miles
  Connect »

Recruitment Status: Open


Brief Description Eligibility Contact Research Team


Receive Emails About New Clinical Trials!

Sign up for our FREE service to receive email notifications when clinical trials are posted in the medical category of interest to you.