The general aim of the present study is to test a cell therapy with third-party allogeneic ex-vivo expanded MSCs as a strategy to induce tolerance in liver transplant recipients. MSCs will be prepared accordingly to established protocols , starting from diagnostic samples of bone marrow aspirates (2-5 mL) or using the remnants in the bag and filter at the end of the bone marrow infusions. From these samples, MSCs will be expanded in GMP approved facilities and used for the present study in patients undergoing liver transplantation.
Condition | Liver Transplant Rejection |
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Treatment | mesenchymal stromal cells |
Clinical Study Identifier | NCT02260375 |
Sponsor | Monia Lorini |
Last Modified on | 22 January 2021 |
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