Predictive Clinical and Biological Parameters in Acute Leukemia Myelodysplastic Syndromes and Myeloproliferative Disorders-HEMATO-BIO-IPC-2013-015
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- STATUS
- Recruiting
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- End date
- May 22, 2024
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- participants needed
- 650
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- sponsor
- Institut Paoli-Calmettes
Summary
HEMATO-BIO-IPC-2013-015 is a monocenter prospective longitudinal study. Our aim is to define predictive clinical and biological factors in acute leukemia, myelodysplastic syndromes and myeloproliferative disorders by using genomics, genetics and epigenetics, in vitro and in vivo drug sensitivity studies,and translational immonulogy and immunomonitoring studies.
HEMATO-BIO primary outcome measure is to identify molecular, genomic and epigenetic, pharmacologic and immunophenotypic alteration in acute leukemia, myelodysplastic syndromes and myeloproliferative disorders by collecting, at diagnosis and/or complete remission and/or
- relapse
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- tumor samples: marrow aspiration, blood sampling.
- non-tumor samples: skin biopsy, buccal swab . from 650 patients treated at our cancer center.
Details
| Condition | Bone marrow disorder, Preleukemia, MYELOPROLIFERATIVE DISORDER, MYELODYSPLASTIC SYNDROME, Myelodysplastic Syndromes (MDS), Acute Leukemia, Myeloproliferative Neoplasms, myelodysplastic syndromes, myeloproliferative neoplasm, myeloproliferative disorders, myelodysplastic syndrome (mds), acute leukemias |
|---|---|
| Treatment | blood sampling, Skin Biopsy, Buccal swab, Bone marrow aspirate |
| Clinical Study Identifier | NCT02320656 |
| Sponsor | Institut Paoli-Calmettes |
| Last Modified on | 22 January 2021 |
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