Predictive Factors and Autonomy Level Change

  • End date
    Nov 5, 2027
  • participants needed
  • sponsor
    Hospices Civils de Lyon
Updated on 5 July 2021
cognitive impairment
alzheimer's disease
behavioural disorders


The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The investigators aimed at developing a database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative personal and with the University hospital computer science department. The main objective is to study the predictive factors associated with the change of functional autonomy level, measured every 6 months to 12 months by phone, in a Memory Clinic. The study population would consist in about 1000 patients with ADRD. The length of follow-up of each patient will be 3 years.

Condition Memory impairment, Memory Problems, impair memory, bad memory, disturbance of memory
Treatment The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6
Clinical Study IdentifierNCT02302482
SponsorHospices Civils de Lyon
Last Modified on5 July 2021


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Inclusion Criteria

Patients who undergo a medical visit in the Memory Clinic for the 1st time
Patients living at home or in housing
Patients with memory impairment, at all stage of the disease

Exclusion Criteria

Patients in institution
Patients under legal protection
Patients with a hearing or visual impairment, which dot not allow to carry out the examination
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