Last updated on March 2019

Novel Lung Functional Imaging for Personalized Radiotherapy

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Brief description of study

The primary objective of this study is to assess the safety and feasibility of personalized radiotherapy with four-dimensional (4D) computed tomography (CT)-based pulmonary ventilation imaging, which selectively avoids irradiating highly-functional lung regions.

Detailed Study Description

In this clinical trial, we will assess the safety and feasibility of 4D CT ventilation image-guided personalized radiotherapy. We will deliver personalized radiotherapy treatments that selectively avoid irradiating highly-functional lung regions for lung cancer patients, and follow up patients to assess the safety and feasibility. The primary hypothesis to be tested is: 4D CT ventilation image-guided personalized radiotherapy can be delivered safely for lung cancer.