Last updated on March 2018

The Tolerability and Effects of AZD0530 in Individuals With or Without a Family History of Alcoholism

Brief description of study

Functional neuroimaging of alcoholism vulnerability: glutamate, reward, impulsivity, and Pavlovian-to-instrumental transfer (PIT), part II Saracatinib

Detailed Study Description

To assess the effect of oral AZ D0530 at various doses on neuroimaging parameters associated with various forms of impulsivity mediated through glutamate-dopamine interactions, as ascertained through functional magnetic resonance imaging. -- --NOTE-- AZD0530 dosage of 50mg was discontinued by manufacturer. Adjustments were made to account for the removal of the 50mg dosage in all arms of the study.

Clinical Study Identifier: NCT02262026

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Hartford Hospital

Hartford, CT United States
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