Last updated on February 2018

A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Artificial respiration | ADULT RESPIRATORY DISTRESS SYNDROME
  • Age: Between 18 - 95 Years
  • Gender: Male or Female

Inclusion Criteria:

  • ICU patients without ARDS and under mechanical ventilation for less than 24 hours
  • Patients within the first 24 hours after onset of moderate to severe ARDS according to the 2012 Berlin definition (ARDS group)

Exclusion Criteria:

  • - Pregnancy
  • Acute exacerbation of diabetes (ketoacidosis, hyperosmolar hyperglycemic state)
  • Patient under mechanical ventilation for > 7 days
  • Dialysis-dependent chronic renal failure
  • Alzheimer's disease
  • Amyloidosis
  • Evolutive neoplastic lesion
  • Chronic pulmonary disease requiring long-term oxygen therapy or mechanical ventilation
  • Chemotherapy treatment in the last 30 days
  • Severe neutropenia (<0.5 G/l)

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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