Cardiac Function and Exercise Capacity in Pulmonary Arterial Hypertension

  • End date
    Dec 22, 2022
  • participants needed
  • sponsor
    Centre Hospitalier Universitaire de Saint Etienne
Updated on 22 December 2021


Pulmonary Arterial Hypertension is characterized by a progressive increase in pulmonary vascular resistance inducing shortness of breath and exercise intolerance. We aim to correlate cardiac function (evaluated at rest by right heart catheterism and RMN) to exercise capacity (evaluated by endurance time at 75% of maximal workout), in prevalent patients with pulmonary arterial hypertension, and their evolution at three and twelve months.

Condition Pulmonary Arterial Hypertension
Treatment Rehabilitation
Clinical Study IdentifierNCT02579954
SponsorCentre Hospitalier Universitaire de Saint Etienne
Last Modified on22 December 2021


Yes No Not Sure

Inclusion Criteria

Adult patients
Patients with Pulmonary Arterial Hypertension (idiopathic, heritable or due to anorexigens)
Prevalent cases of pulmonary artery hypertension (≥ 6 months) confirmed by right heart catheterism
Stable for at least 3 months
Written consent

Exclusion Criteria

Patients unable to proceed with six-minute walk test or CPET, or with contra-indication to exercise evaluation (syncope, low cardiac index, etc)
Exercise induced abnormality (evaluated during the initial CPET) precluding to further evaluation
Clear my responses

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